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KMID : 0363320010220040703
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Journal of Korean Oriental Internal Medicine
2001 Volume.22 No. 4 p.703 ~ p.707
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Effects on the secretion of Gastrin and Uropepsin of rats treated with Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex
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Kim Byung-Woo
Kim Sung-Ook
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Abstract
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Each decoction of Coptidis Rhizoma, Scutellariae Radix and Phellodendri Cortex was orally administrated to the rates. And the effects on the Gastrin and Uropepsin secretions were observed.
The results were as follows:
1. The effects on the secretio of Gastrin in the experimental groups administrered each with Coptidis Rhizoma and Scutellariae Radix comparing with the normal group, showed signficant values P<0.05, P<0.02, P<0.01 and P<0.001 separately. However the group medicated with Phellodendri Cortex showed significant values only 30 minutes after the administration.
2. Uropepsion level in the experimental group administered each with Coptidis Rhizoma and Phellodendri Cortex, comparing with the normal group, showed highly significant statistic values (P<0.001). Another experimental group medicated with Scutellariae Radix showed significantly statistical values (P<0.001) 240 minutes after the administration.
3. According to the above mentioned results it was onculuded tat the secretion of Gastrin in plasma and Uropepsin content of urine in albino rats treated with Coptiodis Rhizoma decoction were remarkaby increased as comparing with Scutellariae Radix and Phellodendri Cortex decoction.
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KEYWORD
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Coptidis Rhizoma, Scutellariae Radix, Phellodendri Cortex, GASTRIN, UROPEPSIN
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